Archaeological studies carried out since the beginning of the 21st century show that the number of Paleolithic sites in the Central Highlands is very large. This is an invaluable, non-renewable heritage resource that plays a great role for scientific research - education, tourism exploitation, and sustainable socio-economic development. In fact, at present, the conservation and exploitation of the values ​​of the Paleolithic relics depends on the attention, investment level and approach of the localities; there are still many shortcomings and have not been implemented. Effectively, there is a great need for conservation planning and sustainable development in regional linkage and integration. Conservation activities and partly exploiting the value of a number of Paleolithic sites have been carried out to a certain extent, but there is a lack of in-depth studies on the current status of conservation and value exploitation of Paleolithic sites in the Central Highland. This article introduces the potential of Paleolithic sites, the current status of conservation and exploitation of relic values ​​for sustainable socio-economic development in the Central Highlands.