Di-n-butyl phthalate (DBP) is a chemical compound belonging to the Phthalates family and is commonly used in various modern industries for multiple purposes. It is employed as an additive for adhesive materials. DBP can dissolve in various organic solvents such as alcohol, ether, and benzene. Additionally, it is used as a corrosion inhibitor and is added as an auxiliary agent to increase the flexibility and durability of rubber (Williams et al., 2016). Phthalates are not chemically bonded to polymer chains by covalent bond but rather embed themselves among the polymer chain molecules, making them prone to leaching or vaporizing into the air and easily exposed to the environment (U.S, 2012). Under hot and sunny conditions, particularly in the high-temperature regions of the Central area, the rate of DBP vaporization increases, posing a higher risk to the health of laborers. In order to assess worker exposure level, individual worker exposure dose sampling of DBP concentration in the breathing zone of 200 workers working at stages where DBP arises in some processing facilities rubber in the Central Region were conducted. The highest recorded DBP concentration was 0.1604 mg/m3 in the curing area of Facility 2 (CS2) in Quang Nam. Workers in different production areas had varying levels of DBP exposure. Exposure to DBP compounds can occur through inhalation in areas where phthalates are used. The results collected through the assessment of current DBP exposure conditions at the research facilities presented and discussed in this paper serve as the basis for developing health protection solutions for workers.